Homopiperazine (Hexahydro-1,4-diazepine)
نویسندگان
چکیده
The X-ray structure of the title compound has been determined for first time. Data on its 1H–13C-NMR coupling constants and 15N-NMR spectrum are also given.
منابع مشابه
N-substituted homopiperazine barbiturates as gelatinase inhibitors.
Matrix metalloproteinases are implicated in a wide range of pathophysiological processes and potent selective inhibitors for these enzymes continue to be eagerly sought. 5,5-Disubstituted barbiturates hold promise as inhibitor types being stable in vivo and relatively selective for the gelatinases (MMP-2 and MMP-9). In this paper we describe the synthesis of 5-piperazine and -homopiperazine sub...
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In the title compound, (C(5)H(14)N(2))[Co(H(2)O)(6)](2)(SO(4))(3), the cationic framework is built up of mixed organic-inorganic fragments, namely [Co(H(2)O)(6)](2+) and [C(5)H(14)N(2)](2+). The [Co(H(2)O)(6)](2+) cations form unconnected octa-hedra. Sulfate anions inter-calated between cationic species connect them via N-H⋯O and O-H⋯O hydrogen bonds and electrostatic inter-actions.
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Inhibitors of myosin light chain kinase, 1-(5-chloronaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride (ML-9) and 1-(5-iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride (ML-7), induced Nitroblue tetrazolium reducing activity, lysozyme activity and morphological maturation of human monoblastic U937, THP-1 and promyelocytic HL-60 cells, but not of erythroblastic K...
متن کاملBis(homopiperazine-1,4-diium) cyclotetraphosphate–telluric acid (1/2)
The title compound, 2C(5)H(14)N(2) (2+)·P(4)O(12) (4-)·2Te(OH)(6), involves doubly protonated homopiperazinium cations, cyclo-tetra-phosphate anions and telluric acid mol-ecules. The framework possesses very large channels wherein the organic cations reside. A network of O-H⋯O, N-H⋯O and C-H⋯O hydrogen bonds consolidates the crystal packing.
متن کامل2,4-Diphenyl-4,5-dihydro-3H-pyrido[2,3-b][1,4]diazepine
The asymmetric unit of the title compound, C(20)H(17)N(3), contains two crystallographically independent mol-ecules (A and B). In mol-ecule A, the two benzene rings form dihedral angles of 74.12 (7) and 7.83 (7)° with the pyridine ring, while in mol-ecule B these angles are 77.48 (7) and 21.50 (7)°. The seven-membered heterocyclic ring adopts a boat conformation in both mol-ecules. In the cryst...
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ژورنال
عنوان ژورنال: Molbank
سال: 2021
ISSN: ['1422-8599']
DOI: https://doi.org/10.3390/m1200